Dr. Renata Pasqualini and Dr. Wadih Arap
Department of Genitourinary Medical Oncology–Rsch 1515 Holcombe Blvd., Unit 0018-1, Room B7.4923 Houston, Texas 77030

Abstract:

We have developed in vivo phage display, a functional peptide screening established in animal models and later in patients. Isolation of homing peptides enables subsequent identification of tissue-specific receptors. Systematic implementation of this strategy will lead to the construction of a comprehensive map of vascular markers in each organ, tissue, or disease, and may result in a new pharmacology.